2. DO YOU HAVE AN IDEA OF WHAT ARE THE MOST SERIOUS AND DISABLING CONSEQUENCES OF DIABETES?

The most invalidating consequence of diabetes.
Diabetics who are affected by PAD (peripheral arterial disease) have a higher risk of mortality compared to those without PAD due to the coexistence of coronary disease (CAD) that is often silent and difficult to detect. Limiting the treatment to the peripheral arteriopathy only, highly exposes the patient to the risk of an undiagnosed coronary or carotid disease, normally easily treated without open surgery. For instance, if the patient with PAD is managed without cardiological and internal medicine consultancies, the risk of unforeseen cardiovascular complications is elevated.
Major limb amputation, different from minor, is a very traumatic event for the patient. The consequences are not limited the patient disability only and involving the whole family, but influences the patient’s life expectancy too. Lower limb amputation is penalized by a concrete perioperative mortality risk and in addition is associated to a poor survival rate. This is because the frequent coexistence of cardiovascular and cerebrovascular disease, with 2 year survival rate is identical to patients with lung cancer.
The battle against leg amputations is therefore crucial for patient’s survival: due to the frequent bilateral disease distribution, only 15% of leg amputees will be able to walk again using limb prosthesis.


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